When it comes to heart health, finding the best hospital for surgery is critical. South Carolina is home to a number of highly-rated hospitals offering advanced heart surgery procedures, specialized care, and cutting-edge technology. Whether you’re seeking life-saving surgery or a second opinion, this list of the Top 20 Best Heart Surgery Hospitals in South Carolina in 2025 will guide you to the right medical facility for your needs.
1. Medical University of South Carolina (MUSC) Health, Charleston
MUSC Health is consistently ranked among the best in the state and nation for cardiovascular care. Their Heart and Vascular Center offers comprehensive heart surgery services, including coronary artery bypass grafting (CABG), valve replacement, and heart transplants. With a focus on patient-centered care, MUSC is renowned for its expertise in complex heart surgeries.Key Highlights:- Accredited by the American Heart Association (AHA) for heart surgery excellence
- Comprehensive heart failure program
- Research-driven treatments and advanced technology
2. Prisma Health – Upstate, Greenville
Prisma Health in Greenville is known for its excellent heart surgery program. The Heart Institute provides a range of services from minimally invasive procedures to complex surgeries. They are especially recognized for their care in coronary artery disease, atrial fibrillation surgery, and valve repairs.Key Highlights:- High success rates in coronary artery bypass surgeries
- Nationally recognized for their cardiac rehabilitation program
- State-of-the-art hybrid operating rooms
3. Roper St. Francis Healthcare, Charleston
Roper St. Francis Healthcare is a leader in heart surgery, offering cutting-edge treatments and a team of skilled cardiac surgeons. Their Cardiac Surgery Program is known for both surgical excellence and compassionate care, making them one of the top hospitals in the state.Key Highlights:- Specializes in minimally invasive heart surgery techniques
- Award-winning heart failure treatment program
- Collaborative care involving multidisciplinary teams
4. Spartanburg Regional Healthcare System, Spartanburg
With a team of highly experienced surgeons and cardiologists, Spartanburg Regional offers comprehensive cardiac care, including heart surgery. The hospital’s Heart Center is widely regarded for its excellent results in coronary artery bypass surgery and valve replacements.Key Highlights:- A leader in cardiac catheterization and interventional procedures
- Focused on both inpatient and outpatient heart care
- Community-oriented programs promoting heart health
5. Lexington Medical Center, West Columbia
Lexington Medical Center provides world-class cardiac care in a community-focused setting. The Heart & Vascular Center provides various surgical options, such as minimally invasive heart surgery, coronary artery bypass, and valve repair or replacement.Key Highlights:- Emphasize the use of minimally invasive techniques to shorten recovery time.
- Well-established heart failure program
- Nationally recognized for exceptional patient care and outcomes
6. Greenville Memorial Hospital, Greenville
Part of the Prisma Health system, Greenville Memorial is a top-rated heart surgery hospital known for its innovative approach to cardiovascular care. They offer a range of heart surgeries, including coronary artery bypass surgery, heart valve surgeries, and innovative robotic-assisted surgeries.Key Highlights:- Focus on advanced cardiovascular interventions
- Robotic-assisted surgeries with reduced recovery times
- A high-volume center for heart surgery
7. Bon Secours St. Francis Health System, Greenville
Bon Secours St. Francis Health System provides a wide variety of heart surgery options, including procedures for heart disease, heart failure, and atrial fibrillation. Their comprehensive cardiac care includes innovative treatments, cutting-edge technology, and personalized recovery plans.Key Highlights:- Recognized for exceptional outcomes in open-heart surgeries
- Award-winning heart failure care and research
- Comprehensive cardiovascular rehabilitation services
8. Charleston Area Medical Center, Charleston
Located in Charleston, this hospital is known for its excellent cardiac care and heart surgery services. The Heart and Vascular Center specializes in the treatment of complex heart conditions and offers state-of-the-art surgical options for coronary artery disease, valve disease, and more.Key Highlights:- Multidisciplinary approach to heart care
- Advanced heart valve surgery and replacement options
- Focus on minimally invasive heart surgery techniques
9. MUSC Health – Lancaster, Lancaster
The MUSC Health Lancaster campus plays a crucial role within the MUSC Health system. With access to the same specialized cardiovascular team as their Charleston facility, patients receive high-quality heart surgery services in a more community-based setting.Key Highlights:- Access to top MUSC cardiologists and surgeons
- Advanced diagnostics and cardiac surgery options
- Comprehensive rehabilitation services post-surgery
10. McLeod Regional Medical Center, Florence
McLeod Regional Medical Center is a premier healthcare provider in the Pee Dee region. Their Heart and Vascular Institute offers comprehensive cardiovascular care, including coronary artery bypass surgery, valve surgery, and treatment for arrhythmias.Key Highlights:- High success rates in coronary artery bypass surgery
- Renowned for their heart failure management program
- State-of-the-art imaging and diagnostic capabilities
11. Trident Medical Center, Charleston
Trident Medical Center provides a comprehensive array of heart surgery services, including coronary artery bypass surgery, heart valve repair, and aortic surgery.Their cardiac team is well-known for their expertise and commitment to patient care.Key Highlights:- Specializes in minimally invasive heart surgeries
- Focus on holistic patient care and post-operative rehabilitation
- Accredited by the American College of Cardiology
12. Columbia VA Health Care System, Columbia
For veterans requiring heart surgery, the Columbia VA Health Care System offers excellent cardiovascular care. Their specialized team offers comprehensive heart surgery treatments for veterans dealing with heart disease, including coronary artery bypass and valve surgery.Key Highlights:- Veterans’ health services with specialized heart care
- Close collaboration with cardiologists and surgeons
- Focus on veteran-centric rehabilitation
13. Piedmont Medical Center, Rock Hill
Piedmont Medical Center is recognized for its exceptional cardiovascular care in the Rock Hill area. Their heart surgery services encompass both minimally invasive techniques and traditional open-heart surgeries.Key Highlights:- Excellent cardiac surgery outcomes and low complication rates
- Focus on patient-centered care and support
- State-of-the-art diagnostic imaging for heart disease
14. Aiken Regional Medical Centers, Aiken
Aiken Regional Medical Centers offers a comprehensive Heart & Vascular Center that provides heart surgery services such as coronary artery bypass and valve replacement. The hospital is well-regarded for its high-quality care and community-centered approach.Key Highlights:- Focus on personalized treatment plans for heart surgery
- Comprehensive post-surgery care and rehabilitation
- Collaborative heart team for multidisciplinary care
15. East Cooper Medical Center, Mount Pleasant
Part of the Roper St. Francis Health System, East Cooper Medical Center offers exceptional cardiac care, including heart surgery. The hospital’s experienced surgeons and cardiologists work together to provide high-quality care for heart patients.Key Highlights:- Cutting-edge diagnostic tools and surgery options
- Patient-focused care and advanced treatment protocols
- High success rate for complex surgeries
16. Rural Health Medical Services, Orangeburg
Offering heart surgery services in the rural communities of South Carolina, Rural Health Medical Services in Orangeburg ensures that residents have access to world-class cardiovascular care. Their skilled team specializes in treating heart disease and conducting surgeries like coronary artery bypass grafting.Key Highlights:- Focus on heart health education and community outreach
- Affordable and accessible heart surgery services
- Dedicated rehabilitation programs
17. Conway Medical Center, Conway
Conway Medical Center offers advanced heart surgery services, including coronary artery bypass grafting, aortic valve replacements, and minimally invasive surgeries. Their team is committed to providing expert care and improving patient outcomes.Key Highlights:- Known for excellent cardiac surgical outcomes
- Comprehensive heart failure care
- Modern rehabilitation and recovery programs
18. Coastal Carolina Hospital, Hardeeville
Coastal Carolina Hospital is dedicated to providing high-quality heart care to the coastal region of South Carolina. Their cardiac surgery team performs a wide range of procedures and uses the latest technology for patient diagnosis and treatment.Key Highlights:- Comprehensive cardiac care services
- Low complication rates and high patient satisfaction
- Multidisciplinary approach to heart health
19. Blue Ridge Health System, Travelers Rest
Blue Ridge Health System offers specialized heart surgery treatments for residents of the upstate region of South Carolina. Their Heart Center is known for its innovative approaches to cardiac surgery and patient rehabilitation.Key Highlights:- Specialized heart surgery programs tailored to patient needs
- Excellent cardiac rehabilitation services
- High patient satisfaction with surgical outcomes
20. The Regional Medical Center, Orangeburg
Located in Orangeburg, The Regional Medical Center offers comprehensive heart surgery services, including treatments for heart disease, arrhythmias, and coronary artery disease. Their heart surgeons are highly skilled in using both traditional and advanced surgical techniques.Key Highlights:- Highly rated for coronary artery bypass surgery
- Strong focus on preventive care and patient education
- Collaborative care model for heart patients
